Frontiers Glutathione metabolism as a key regulator of oxidative hippocampal injury in sepsis associated encephalopathy: an integrated proteomics and metabolomics study Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Antioxidant Therapies in Traumatic Brain Injury Frontiers Glutathione deficiency in the pathogenesis of SARS CoV 2 infection and its effects upon the host immune response in severe COVID 19 disease