You Need More Riboflavin with G6PD Deficiency! G6PDHelp.com Pharmacological targeting of glucose 6 phosphate dehydrogenase in human erythrocytes by Bay 117082, parthenolide and dimethyl fumarate Scientific Reports Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst The Guardian of the RBC: Mastering G6PD Deficiency! #USMLEStep1 #MedEd #Biochemistry #Hematology #G6PD #HemolyticAnemia #Step1Prep #HighYield #MedSchool #BiteCells #HeinzBodies #Genetics #FutureDoctor #StudyGram #MedTwitter https HEMOLYTIC ANEMIA G6PD Deficiency causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione (