Ehlers Danlos syndrome MEpedia EDS Info Ehlers Danlos Syndromes Aotearoa New Zealand Frontiers Mechanobiology in the Comorbidities of Ehlers Danlos Syndrome Could a vitamin deficiency cause 'double jointedness' and hypermobile Ehlers Danlos syndrome? Ehlers Danlos syndrome (EDS) is a group of 13 related genetic (heritable) connective tissue disorders. EDS, particularly the hypermobile type (hEDS), frequently overlaps with Postural Orthostatic Tachycardia Syndrome (POTS) and Mast Cell Activation Kyphoscoliotic Ehlers Danlos syndrome (kEDS) is a rare type of EDS and symptoms include muscle hypotonia, kyphoscoliosis which is congenital or early onset, as well as generalised joint hypermobility. kEDS is caused by