Oral Melanotic Macule: Symptoms and Treatment Skinsight This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Figure 1 from Pigmented lesions of the oral cavity: review, differential diagnosis, and case presentations. Semantic Scholar Melanocytic Lesions A Guide to Clinical Differential Diagnosis of Oral Mucosal Lesions Continuing Education Course dentalcare.com Melanotic macule MEDizzy What Caused These Multiple Hyperpigmented Macules of the Mouth?