What Novo Nordisk's disappointing trial results mean for the obesity drug market Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Weight loss: New drug CagriSema leads to 14% weight loss in trial Cagrilintide (AM833) Long acting amylin analog. Beta cells make TWO hormones: insulin and amylin. Amylin slows stomach emptying and reduces appetite. Cagrilintide is a long acting synthetic amylin designed for once weekly dosing Novo Nordisk takes a hit as CagriSema underperforms in weight loss Data on Novo Nordisk experimental weight loss drug show mostly mild side effects Reuters
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